Welcome to TITAN: Scaling Computational Neuroscience & Neuro-AI

We are proud to welcome you to the official platform of the TITAN Team. Rooted at the intersection of advanced neurosurgery, computational linguistics, and artificial intelligence, the TITAN laboratory is dedicated to cracking the neural codes of human cognition and language processing. By combining unique clinical insights with cutting-edge machine learning, our mission is to redefine how we observe, decode, and model brain dynamics.

Our research addresses a fundamental scientific challenge: mapping brain activity across multiple spatial scales—ranging from single-neuron multi-unit recordings in surgical settings to non-invasive whole-brain dynamics via MEG, EEG, and fMRI. Through these rich, multi-scale datasets, TITAN builds predictive computational models that open new frontiers for both cognitive neuroscience and translational clinical applications.

Lab Leadership

Dr. Pierre Bourdillon

Founder & Lead Investigator, Neurosurgeon

Over the next five years, Dr. Pierre Bourdillon is leading the expansion of the TITAN research team, aiming to build next-generation encoding and decoding architectures. Navigating between the operating room and computational data labs, his vision focuses on scaling clinical infrastructure to capture high-density data. This framework allows the lab to engineer innovative solutions for speech restoration, advanced brain-computer interfaces (BCIs), and international data-sharing collaborations.

Our Core Research Axes

The TITAN lab operates as a highly integrated, interdisciplinary ecosystem structured around four primary fields of expertise:

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Machine Learning & Foundation Models: Developing self-supervised and contrastive deep learning architectures capable of processing massive intracranial (iEEG) datasets without manual feature engineering, pioneering new baselines for neural decoding.

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Clinical Physiology & Neuropaediatrics: Studying speech and cognitive trajectories within the child brain, evaluating the direct impact of drug-resistant epilepsy on language networks, and improving surgical planning through computational mapping.

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Computational Linguistics & Neuroinformatics: Mapping the hierarchical, temporal structures of language within cortical patches, comparing biological linguistic processing with state-of-the-art language models (LLMs).

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Strategic Development & Consortia Management: Coordinating multinational research efforts, ensuring robust data management pipelines, and bridging scientific discoveries with large-scale collaborative programs like the Digital Brain Project.

Navigate through our dedicated team tabs to discover our researchers’ specific projects, full publication records, and open-source models.